欧阳逸斌徐明△.几种与肿瘤血管生成有关的调控因子研究进展[J].,2012,12(21):4176-4179 |
几种与肿瘤血管生成有关的调控因子研究进展 |
Progress of Studies on Several Regulatory Factors Related to TumorAngiogenesis |
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DOI: |
中文关键词: 肿瘤血管 VEGF MMP EGFR bFGF |
英文关键词: Tumor vascular VEGF MMP EGFR bFGF |
基金项目:湖南省人事厅留学人员择优资助项目(394201001) |
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中文摘要: |
肿瘤血管能够导致肿瘤疯狂生长,也是肿瘤细胞扩散和转移的秘密通道。因此对肿瘤血管的生成的研究就成为了当前研究
的热点。本文对VEGF、MMP、EGFR、bFGF 等重要的促血管生成因子与肿瘤血管生成、生长关系的临床证明、病理组织学研究、基
因学研究以及以此为靶点的药物治疗的研究现状,尤其是中药治疗研究情况作综述。 |
英文摘要: |
Tumor vascular can lead to the crazy growth of tumor, and is also the secret tunnels of cancer cells to spread and
transfer. So study on the generation of tumor vascular become the hot spot of current research. We will review the studies of the relationship
between some important angiogenesis factors like, VEGF, MMP, EGFR, bFGF with tumor vascular production and development
from different aspects, and the studies of the drug therapy to these therapeutic targets, especially Chinese traditional medicine. |
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