| 马晓芹1 朱桂纯1 王艳1△ 温雪松1 于湘珠2.优必清软膏治疗尖锐湿疣的临床疗效观察[J].,2012,12(21):4042-4045 |
| 优必清软膏治疗尖锐湿疣的临床疗效观察 |
| Curative Effects of Youbiqing Ointment on Condyloma Acuminatum |
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| DOI： |
| 中文关键词: 尖锐湿疣 外阴假疣 人类乳头瘤病毒 抗人乳头瘤病毒软膏（优必清软膏） 基因芯片技术 |
| 英文关键词: Condyloma acuminatum Pseudocondyloma Human papilloma viruse Anti- human papilloma viruse Ointment
（Youbiqing Ointment） GeneChip |
| 基金项目: |
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| 中文摘要: |
| 目的：中药复方制剂抗人乳头瘤病毒软膏（优必清软膏）对尖锐湿疣（Condyloma acuminatum,CA）脱疣的疗效、复发和安全性
的评价。方法：采用随机、双盲、平行对照、临床观察，共150 例。尖锐湿疣优必清软膏组(试验组) 60 例，尖锐湿疣足叶草脂液（别
名鬼臼根树脂、疣必治、鬼臼素酯，其活性成分为足叶草酯毒素）组(对照组) 60 例。作为参考选取外阴假疣优必清软膏组30 例与
尖锐湿疣优必清软膏组60 例平行对照。局部外涂覆盖疣体，隔日一次，疗程1-4 周，随访3-6 个月。CA 脱疣疗效、复发率作为观察
指标。不良事件发生情况作为安全评价。结果：试验组和对照组脱疣的有效率为95%和86.67%，两组的复发率为5%和23.33% ,试
验组脱疣疗效高于对照组、复发率低于对照组。结论：优必清软膏治疗CA，疗效显著，复发率低，临床用药安全。优必清软膏无明
显副作用。 |
| 英文摘要: |
| Objective: To evaluate the anti-wart efficacy and relapse rate and safety of anti-wart traditional chinese drug compound
preparation anti- human papilloma viruse Ointment （Youbiqing Ointment）of condyloma acuminatum (CA). Methods: A randomized,
double- blind, parallel controlled clinical observation was carried out. All 150 cases were divided, 60 cases into Condyloma acuminatumYoubiqing
Ointment group ( trial group) and 60 cases into Condyloma acuminatum Podophyllin Fluid （alias Podofilm
Podophyllumresin podophyllotoxin, active constitutent to do Podophyllotoxin）group (control group). conduct and actions collate select
30 cases into Pseudocondyloma Youbiqing Ointment group and 60 cases into Condyloma acuminate Youbiqing Ointment group. The
wart was coated with local Ointments for course of treatment 1-4weeks and follow-up observation 3-6months. The observation-indexs
were anti-wart efficacy and relapse rate of CA.The safety evaluation were kak-occurrence generate etat of CA. Results: The total
markedly effective rate of anti-wart 95% vs 86.67% and relapse rate of CA 5% vs 23.33% intrial group were superior to those in control
group respectively. Conclusion: Youbiqing Ointment has an evident effect and lower relapse rate and is security in clinical Practice of
condyloma acuminatum. Youbiqing Ointment had no obvious side effect. |
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