文章摘要
刘的1 王敦敬1 张习伦2 陆燕1 王敏1 肖成华1△.帕金森病抑郁的相关因素分析[J].,2012,12(15):2934-2936
帕金森病抑郁的相关因素分析
A Study of Related Factors of Depression in Parkinson Disease
  
DOI:
中文关键词: 帕金森病  抑郁情绪  相关因素
英文关键词: Parkinson's disease  Depression  Related factors
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作者单位
刘的1 王敦敬1 张习伦2 陆燕1 王敏1 肖成华1△ 徐州医学院附属医院神经内科徐州医学院神经病学教研室 
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中文摘要:
      目的:探讨抑郁在帕金森病中(Parkinson's disease, PD )的发生率及其影响因素。方法:对确诊的PD 患者,采用汉密尔顿抑郁 量表(Hamilt depression scale,HAMD)、简易精神状态检查量表(Mini-Mental State Examination,MMSE)及Webster 功能评分量表 进行评定,分析抑郁的发生情况和相关影响因素。结果:PD 伴发抑郁者32 例,抑郁的发生率为49.2 %,病程、文化程度、Webster 评分、MMSE 评分与帕金森抑郁的发生均有统计学意义(P<0.05),年龄、性别、婚姻状况、经济情况与帕金森抑郁的发生均无统计 学意义(P>0.05)。回归分析发现病程和病情严重程度是PD 患者抑郁的危险因素。结论:PD 患者有较高的抑郁发生率,抑郁的发 生可能是社会心理、神经生物学多种因素作用的结果。
英文摘要:
      Objective: To investigate the prevalence of depression in patients with Parkinson's disease and its correlated factors. Methods: For the diagnosed PD patients, evaluated with the Hamilton Depression Rating Scale (HAMD), the mini-mental state examination (MMSE) and the Webster rating scale,analysis of the incidence of depression and related factors. Results: 32 PD patients were associated with depression, and the frequency of depression was 49.2%. There were significant differences in duration of disease, educational level, webster score and MMSE score (P<0.05). There were no statistical relationships between age, gender, marital status and economic situation (P>0.05). Logistic regression analysis demonstrated that the most important predictive factors for depression were duration of disease and severity of disease. Conclusion: The prevalence of depression was high in PD patients, and may be occur for social psychology, neurobiology result of many factors.
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