| 刘的1 王敦敬1 张习伦2 陆燕1 王敏1 肖成华1△.帕金森病抑郁的相关因素分析[J].,2012,12(15):2934-2936 |
| 帕金森病抑郁的相关因素分析 |
| A Study of Related Factors of Depression in Parkinson Disease |
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| DOI： |
| 中文关键词: 帕金森病 抑郁情绪 相关因素 |
| 英文关键词: Parkinson's disease Depression Related factors |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨抑郁在帕金森病中(Parkinson's disease, PD )的发生率及其影响因素。方法：对确诊的PD 患者，采用汉密尔顿抑郁
量表（Hamilt depression scale，HAMD）、简易精神状态检查量表（Mini-Mental State Examination，MMSE）及Webster 功能评分量表
进行评定,分析抑郁的发生情况和相关影响因素。结果：PD 伴发抑郁者32 例，抑郁的发生率为49.2 %，病程、文化程度、Webster
评分、MMSE 评分与帕金森抑郁的发生均有统计学意义（P＜0.05），年龄、性别、婚姻状况、经济情况与帕金森抑郁的发生均无统计
学意义（P＞0.05）。回归分析发现病程和病情严重程度是PD 患者抑郁的危险因素。结论：PD 患者有较高的抑郁发生率，抑郁的发
生可能是社会心理、神经生物学多种因素作用的结果。 |
| 英文摘要: |
| Objective: To investigate the prevalence of depression in patients with Parkinson's disease and its correlated factors.
Methods: For the diagnosed PD patients, evaluated with the Hamilton Depression Rating Scale (HAMD), the mini-mental state
examination (MMSE) and the Webster rating scale,analysis of the incidence of depression and related factors. Results: 32 PD patients
were associated with depression, and the frequency of depression was 49.2%. There were significant differences in duration of disease,
educational level, webster score and MMSE score （P＜0.05）.
There were no statistical relationships between age, gender, marital status
and economic situation （P＞0.05）.
Logistic regression analysis demonstrated that the most important predictive factors for depression
were duration of disease and severity of disease. Conclusion: The prevalence of depression was high in PD patients, and may be occur for
social psychology, neurobiology result of many factors. |
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