| 张帷1 司全金1△ 李开亮1 郭晓东2 赵晓宁1 潘静坤1.不同年龄急性冠脉综合征患者血脂代谢临床特点对比分析[J].,2012,12(11):2099-2103 |
| 不同年龄急性冠脉综合征患者血脂代谢临床特点对比分析 |
| The Analysis of Blood Lipid and C-reactive Protein in Different Ages Patientswith Acute Coronary Syndrome |
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| DOI： |
| 中文关键词: 急性冠脉综合征 C 反应蛋白 脂类及降血脂药 危险因素 |
| 英文关键词: Acute coronary syndrome C- reactive protein Lipid and antilipemic agents Risk factors |
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| 中文摘要: |
| 目的：对比研究不同年龄急性冠脉综合征患者急性期血脂代谢特点及相关因素变化，探讨血脂代谢在不同年龄急性冠脉综
合征发生过程中的作用及临床意义。方法：222 例急性冠脉综合征（ACS）患者及119 例稳定型心绞痛（SAP）患者共341 例按照年
龄分为3 组，<60 岁为非老年组共68 人，其中ACS 组33 人，SAP 组35 人；60-74 岁为普通老年组共67 人，其中ACS 组34 人，
SAP 组33 人；≥75 岁为高龄老年组共206 人，其中ACS 组155 人，SAP 组51 人。详细记录其基线资料并测定其血脂各项指标
（包括TC、TG、LDL-C、HDL-C）及CRP。结果：与SAP 患者比较，非老年人组及普通老年人组ACS 患者LDL-C、CRP 均显著升高；
高龄老年人ACS 患者LDL-C 水平无显著升高，但HDL-C 显著降低，CRP 显著升高，差异均具有统计学意义（P<0.05），LDL-C 虽
无显著升高，但未达指南要求水平。各组之间TC、TG 之间差异无统计学意义(P>0.05)。结论：脂代谢异常在不同年龄ACS 患者的
发生过程中均有重要作用，老年ACS 患者中，除了应关注脂代谢紊乱外，还应该关注高血压、糖尿病等危险因素。 |
| 英文摘要: |
| Objective: To investigate the characteristics of blood lipid and CRP in different ages patients with acute coronary syndrome
（ACS）, and to discuss its clinic effect in progress of ACS. Methods: 341 CAD patients were divided into non-elderly group (<60
years,n=68), common old group(between 60 to 74 years,n=67) and very old group (≥75 years,n=206) according the age.Every age group
was divided into ACS group and SAP group. The clinical formations and results of the levels of blood lipid (contain TC, TG, LDL-C,
HDL-C), CRP were analyzed by contrast method. Results: Compared with SAP group, the level of LDL-C, CRP in ACS group was significant
higher in young men and common old group. However, in very old group, the level of HDL-C was significant lower, and the level
of CRP was significant higher than SAP group (P<0.05). There was no difference in levels of TC, TG between the groups of ACS and
SAP（P>0.05）. Conclusions: Lipid disorders play an important role in the progress of ACS. In very old group of ACS patients, we should
pay more attention to the risk factors of hypertension and diabetes mellitus except for lipid disorders. |
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