| 丁连安牛冬光邵长春曲林林孙立群陈双喜.多原发癌[J].,2012,12(9):1738-1741 |
| 多原发癌 |
| Multiple PrimaryMalignancies |
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| DOI： |
| 中文关键词: 多原发癌 恶性肿瘤 遗传易感性 治疗 |
| 英文关键词: Multiple Primary Malignancy Malignancy Genetic Predisposition Management |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨多原发癌的病因、临床特点及其诊治。方法：回顾性总结分析了一组普通外科多原发癌病人的资料，并结合文献
进行了分析。结果：本组77 例多原发癌，占同期普通外科住院病人的1.33%(77/5768),半数以上发生于65 岁及以上的老年人。胃
肠道多原发癌占81.8%。其发生主要与下列因素有关：基因缺陷因素（遗传易感性）、环境因素、治疗所致（如放、化疗）、免疫缺陷、
老龄。结论：多原发癌近年呈增加趋势，对于肿瘤病人的诊治，不要忽略了同时性癌的可能；手术仍是多原发癌实体瘤主要而有效
的治疗手段。 |
| 英文摘要: |
| Objective: To investigate the etiology, clinical characteristics, and management of multiple primary malignancies
(MPM). Methods: A group of 77 patients with MPMwere treated in the general surgery department from May 2002 to April 2007. Results:
These patients accounted for 1.3% of hospitalized patients (77/5768) in the general surgery department from May 2002 to April 2007.
Half of them were more than 65 years old; gastrointestinal MPM accounted for 81.8% of the cases (63/77). The related factors are genetic
defects, environmental factors, medical treatments (such as radiotherapy and chemotherapy), immunity defects and advanced age. Conclusion:
The incidence of MPM is increasing in recent years.The possibility of synchronous/metachronous carcinomas should not be
overlooked during treatment for cancer or when patients return for further consultation. Resection is the primary therapeutic measure for
solid MPM tumors. |
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