黄承乐黄红华黄荣幸农世泽岑柳仙.IL-6,IL-8 的检测在鉴别良恶性胸水中的诊断价值分析[J].,2012,12(9):1707-1709 |
IL-6,IL-8 的检测在鉴别良恶性胸水中的诊断价值分析 |
Differential Diagnostic Value of Determination of IL-6, IL-8 in Serum andPleural Effusion between Benign and Malignant Hydrothorax |
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DOI: |
中文关键词: 白细胞介素6 白细胞介素8 胸水 诊断价值 |
英文关键词: IL-6 IL-8 Hydrothora Differential diagnostic value |
基金项目: |
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中文摘要: |
目的:分析检测血清、胸水中白细胞介素6(IL-6)、白细胞介素8(IL-8)水平对良恶性胸水的鉴别诊断价值。方法:采用酶联免
疫吸附试验(ELISA)检测32 例良性胸水患者和40 例恶性胸水患者血清及胸水中IL-6、IL-8 水平,以及30 例健康体检者血清中
IL-6、IL-8 水平。结果:良性胸水组及恶性胸水组血清IL-6、IL-8 水平均显著高于正常对照组,差异具有统计学意义(P<0.05);与恶
性胸水组比较,良性胸水组胸水及血清中IL-6、IL-8 水平升高更为显著(P<0.05),良性胸水组IL-6、IL-8 的胸水/ 血清比值也显著
高于恶性胸水组,差异具有统计学意义(P<0.05)。结论:胸水及血清中IL-6、IL-8 的检测对良、恶性胸水患者具有鉴别诊断意义。 |
英文摘要: |
Objective: To explore the differential diagnosis value of determination of IL-6, IL-8 in serum and pleural effusion between
benign and malignant hydrothora. Methods: The levels of IL-6, IL-8 in serum and pleural effusion of 32 cases with benign hydrothorax,
40 cases with malignant hydrothora were detected, and the levels of IL-6, IL-8 in serum of 30 healthy subjects were detected by ELISA.
Results: The levels of IL-6, IL-8 in serum were significantly increased in cases with benign or malignant hydrothora in comparison with
those of control group, the difference was statistically significant (P<0.05). There were statistically significant differences of the levels
and the pleural effusion/serum ratio of IL-6, IL-8 in serum and pleural effusion between benign and malignant hydrothora (P>0.05). Conclusion:
The levels of IL-6, IL-8 in serum and pleural effusion may be used as an marker in the differential diagnosis of benign and malignant
hydrothora. |
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