| 他维玮1,2 赵曼1,2 孙守员1 哈小琴2△.非小细胞肺癌的治疗方案及影响预后的重要因素[J].,2012,12(5):910-912 |
| 非小细胞肺癌的治疗方案及影响预后的重要因素 |
| Treatment of Non-small Cell Lung Cancer andthe Important Prognostic Factors |
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| DOI： |
| 中文关键词: NSCLC 治疗 预后因素 |
| 英文关键词: NSCLC Therapy Prognosis factors |
| 基金项目: |
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| 中文摘要: |
| 目的：回顾分析各种非小细胞肺癌(non-small cell lung cancer, NSCLC)的治疗方案及影响其治疗预后的因素，为合理制定个
体化的综合治疗方案提供参考。方法：回顾分析近年来NSCLC 治疗的研究报道，分析如病理分期、实验室检查结果（VEGF、
WBC、Hg 等）影响治疗预后的因素，建议相应的治疗对策。结果：1.Ⅰ期、Ⅱ期及部分Ⅲa 期NSCLC 的患者治疗措施首先以手术
治疗为主，同步放化疗比单纯放、化疗及序贯放化疗更能有效改善晚期NSCLC 的预后；2.个体相关因素、肿瘤相关因素和治疗相
关因素影响NSCLC 治疗预后。结论：同步放化疗在晚期NSCLC 的治疗中有重要作用，肿瘤的病理分期、血浆VEGF 浓度是影响
NSCLC 预后的独立因素。 |
| 英文摘要: |
| Objective: To analyze treatment options of non-small cell lung cancer (NSCLC) and the factors affecting the prognosis,
in order to provide a comprehensive reference to develop individualized treatment programs. Methods：Review the recent research
reports of NSCLC treatment. Analyze the role of influencing factors such as tumor staging, laboratory test results (VEGF, WBC, Hg, etc.)
in tumor therapy. Suggest the appropriate therapeutic strategies. Results：1）.
The first treatment option to NSCLC patients with stageⅠ,
Ⅱ, Ⅲa are surgical treatment. Concurrent chemo-radiation is more effective in improving the prognosis of advanced NSCLC than simply
radiotherapy or chemotherapy and sequential chemo-radiation. 2）.
Individual factors, tumor-associated factors and treatment-related
factors affect the prognosis of NSCLC treatment. Conclusion：Concurrent chemo-radiation has an important role in the treatment of
advanced NSCLC. Tumor staging and plasma VEGF concentration are independent prognosis factors of NSCLC. |
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