| 梁小锋1 雷续虎2 周龙虎3.自杀行为的生物遗传因素研究[J].,2012,12(4):739-741 |
| 自杀行为的生物遗传因素研究 |
| The Research of Gene Polymorphism of Suicidal Behaviar |
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| DOI： |
| 中文关键词: 自杀行为 遗传因素 基因多态性 |
| 英文关键词: Suicidal behaviar Genetic factors Gene polymorphism. |
| 基金项目:国家自然科学基金(30971109)；重庆市自然科学基金(CSTC2009BA5011) |
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| 中文摘要: |
| 自杀是我国15-34 岁人群首位重要的死亡原因。自杀行为的发生与生物学、心理学、社会学等多种因素有关。研究表明自杀
行为确有一定的遗传学基础，近年来自杀行为的生物遗传因素研究发现5-HT 系统相关基因、儿茶酚胺氧位甲基转移酶基因、精
胺/ 精脒乙酰转移酶基因等候选基因单核甘酸多态性与自杀行为有明显关联。有学者认为，自杀行为的遗传学基础可能是附加于
精神疾病的遗传或家庭环境诱导所致。本文就近年来国内外有关自杀的主要相关基因研究发现作一综述。 |
| 英文摘要: |
| Suicidal behaviors are the most complicated ones in human society. Suicide of the people aged between 14 and 35
years is the first cause of death in our country. As to now, we have known the following factors for suicide: psychological，socialogical
and biological. Some study suggests that suicidal behaviors have genetical basics,adhere to mental illness or family circumstances.
Recently, The genetical researches have located some probable genes of suicidal behaviar, Such as 5-HTR2A gene, TPH gene, 5-HTT
gene, MAO gene, COMT gene and SSAT gene.In this article,the author reviewed the articles about the gene polymorphism of suicidal
behaviar. |
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