| 张军芳蒋飞霞张宜夏永祥△.细胞因子与类风湿关节炎的研究进展[J].,2012,12(4):735-738 |
| 细胞因子与类风湿关节炎的研究进展 |
| Progress of the Studies on Relationships between Cytokinesand Rheumatoid Arthritis |
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| DOI： |
| 中文关键词: 类风湿关节炎 白细胞介素 肿瘤坏死因子 基质金属蛋白酶 |
| 英文关键词: Rheumatoid arthritis Interleukin Tumor necrosis factor Matrix metalloproteinases |
| 基金项目: |
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| 摘要点击次数: 819 |
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| 中文摘要: |
| 类风湿关节炎（RA）是一种慢性、多系统的以关节的炎症损害为主要特点的自身免疫性疾病。其发病过程与多种细胞因子有
关，包括TNF-α、IL-1、MMPS、IL-6、IL-17、IL-18 等，这些细胞因子在RA 的发病进程中起了很重要的作用，可作为治疗RA 的新靶
点。 |
| 英文摘要: |
| Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation leading to joint
destruction with systemic involvement. The pathogenesis of rheumatoid arthritis are related to many cytokines, such as TNF-α, IL-1,
MMPS, IL-6, IL-17, IL-18 and so on. It has been confirmed the cytokine-mediated immunity plays a crucial role in the pathoge- nesis of
RA and anti-cytokine therapy has become novel target treatment for RA. |
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