| 严莲珍鲁燕侠赵春艳同军张咏梅△ 邹德勇.鬼臼毒素涂膜剂治疗子宫颈HPV 感染的疗效观察[J].,2012,12(4):716-718 |
| 鬼臼毒素涂膜剂治疗子宫颈HPV 感染的疗效观察 |
| Effect Observation of Podophyllotoxin Film Coating Agent Treating HPVInfection of Cervix |
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| DOI： |
| 中文关键词: HPV 子宫颈 鬼臼毒素酊 鬼臼毒素涂膜剂 |
| 英文关键词: Cervical Podophyllotoxin tincture Podophyllotoxin film coating agent |
| 基金项目:陕西省中医管理局课题(zy18) |
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| 中文摘要: |
| 目的：了解鬼臼毒素涂膜剂治疗子宫颈HPV 感染的疗效。方法：126 例临床诊断证明为子宫颈HPV 感染的患者，随机分为
两组，试验组63 例采用0.5 %鬼臼毒素涂膜剂治疗，对照组63 例单独采用0.5 %鬼臼毒素酊治疗。结果：①痊愈率：试验组与对照
组的痊愈率分别为90.5%、73.00%，两组比较具有统计学学差异(P＜0.05);②复发率：试验组与对照组第12、24 周的复发率分别为
9.52%、28.57%和9.52%、36.51%，两个时段的两组比较均具有统计学差异(P＜0.05)；③不良反应:经随访观察，两组发生了红斑、水
肿、灼热、疼痛、瘙痒、溃疡、渗出等不良反应,其中两组比较试验组红斑、水肿、溃疡、渗出的发生率低于对照组，具有统计学差异
(P＜0.05)。结论：鬼臼毒素涂膜剂能有效治疗子宫颈HPV 感染，并控制复发，副作用小，比采用鬼臼毒素酊治疗的效果好。 |
| 英文摘要: |
| Objective: To understand the efficiency of podophyllotoxin film coating agent treating HPV infection of cervical.
Methods: 126 patients with HPV infection were randomly divided into 2 groups according to random number table. The control group
was given 0.5% Podophyllotoxin Tincture and the experimental group was treated with 0.5% podophyllotoxin film coating agent.
Results: ①Cure rate: The cure rate of test and control groups were 90.5% and 73.00% respectively with statistic difference between the
two groups (p＜0.05); ② Recurrence rate: The recurrence rates of experimental group were 9.52% and 28.57% respectively and 9.52%
and 36.51% respectively with control group on week 12 and week 24 having statistic difference between the two groups; ③Adverse
effects: The two groups occurred erythema, edema, scorching, ache, itching, ulceration, exudation, etc; and the incidence of erythema
edema, ulcer in experimental group was lower than control group. Conclusions: Compared to podophyllotoxin tincture, Podophyllotoxin
film coating agent could effectively cure HPV infection of cervical and control it's recurrence with smaller side effects and better effect. |
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