Objective: The relation of blood uric acid and acute ischemic stroke is researched. Methods: We have selected 100
examples of acute ischemic stroke and health people to compare. The fasting serum uric acid (UA), total cholesterol (TC), triglyceride
(TG), low density lipoprotein (LDL-C) and high density lipoprotein (HDL-C) are measured. At the same time, the carotid artery
ultrasound examination, the NIH Stroke Scale and Barthel index of the case group are calculated. For two groups of Uric acid level with
the index changing of UA, TC, TG, LDL-C, HDL-C at the various levels are compared. The difference among the NIH Stroke Scale,
Barthel index and formation rate of atheromatous plaque in carotid arteries is analyzed. Results: The quantity of the case group and
Control group of fasting serum uric acid, are equal to 46 and 17, respectively. Here the percentages are 46% and 17%. The average
consistency of Serum uric acid are 485.96±76.03(μmoL/L)and 343.12±61.46(μmoL/L). The difference has a statistics. The result of
UA in case group is higher than control group. The compression of the two groups have significant difference (P<0.01). The UA, TC, TG,
LDL-C, HDL-C of case group is more significant than natural group (P < 0.05). For the level of UA in case group, the result of the carotid
artery ultrasound, the NIH Stroke Scale and Barthel index are analyzed. The UA level of patients at case group has parallel relationship
with patients' condition and prognosis, namely the level of UA is high, formation rate of atheromatous plaque in carotid arteries is high,
patients' condition is heavy, and prognosis is bad. Conclusions: Hyperuricemia is important dangerous factor of ischemic stroke, and is
one of synthesis factors preventing ischemic stroke. |