| 杨丽虹黄晓俊△ 金安琴陈平.抑癌基因XEDAR 的研究进展[J].,2011,11(20):3988-3990 |
| 抑癌基因XEDAR 的研究进展 |
| Research Progress in Tumor-suppressor Gene XEDAR |
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| DOI： |
| 中文关键词: XEDAR 基因 抑癌基因 凋亡 肿瘤 |
| 英文关键词: XEDAR Tumor-suppressor gene Apoptosis Tumor |
| 基金项目: |
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| 中文摘要: |
| X - 连锁性外胚层发育不良受体(X-linked ectodermal dysplasia receptor，XEDAR）基因位于人类染色体Xq12，编码的蛋白
XEDAR 作为新近分离出来的肿瘤坏死因子受体家族成员其功能主要涉及细胞增殖、参与细胞分化（胚胎的发育，表皮的分化）、
调亡等。XEDAR 已在多种肿瘤组织中研究，笔者就其基本概念及在肿瘤研究方面的进展进行综述。 |
| 英文摘要: |
| X - linked ectodermal dysplasia receptor(XEDAR), as a recently isolated member of the tumor necrosis factor receptor
family, is encoded by the X - linked ectodermal dysplasia receptor (XEDAR) gene which on the X chromosome .The function of XEDAR
mainly involves cell proliferation , differentiation (embryonic development and differentiation of epidermis), apoptosis, etc. XEDAR has
been studied in a wide variety of tumor tissue, this review is mainly based on its concept and research progress in cancer. |
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