| 季振涛1 王霖1 桂成岩1 靳虎1 杨庆诚2.21 例胫骨近端骨肉瘤保肢治疗临床分析[J].,2011,11(13):2522-2524 |
| 21 例胫骨近端骨肉瘤保肢治疗临床分析 |
| Analysis the Therapy for Resection of Proximal Tibia Bone Osteosarcoma |
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| DOI： |
| 中文关键词: 胫骨 近端 骨肉瘤 关节成形术 置换 |
| 英文关键词: Tibia Proximal Osteosarcoma Anhroplasty Replacement |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨胫骨上端骨肉瘤保肢手术中使用人工关节重建的疗效和并发症。方法：回顾性分析2000 年6 月～2010 年6 月对
21 例胫骨上段骨肉瘤患者行根治性切除人工关节重建手术的临床资料，其中男性13 例, 女性8 例，年龄21-62 岁，平均34.1 岁。
依据Enneking 分期:ⅡA 期12 例、ⅡB 期9 例。均采用广泛性边缘切除手术治疗。所有患者均接受术前、术后化疗。结果：1 例患
者发生术后胫前肌群坏死。所有患者均随访6-72 个月, 平均45.1 个月。ⅡA 期12 例患者中，1 例因肺转移死亡(占8.3%)，局部复
发1 例,行股骨下段截肢，10 例无病生存；ⅡB 期9 例，4 例死亡，5 例存活；Enneking 分期明显影响预后。结论：胫骨上段人工关节
重建对胫骨上段骨肉瘤的保肢治疗具有良好的疗效。 |
| 英文摘要: |
| Objective: To evaluate the efficacy and complications of osteoarticular allografts in the limb salvage of the proximal
tibia .Methods: The clinical data of 21 patients with osteoarticular allografts of the proximal tibia underwent osteoarticular allografts from
June 2000 to June 2010，13 males and 8 females，aged 15-78 years old ( averaged, 34.1years)，were analyzed retrospectivelv. All the
patients underwent the marginal resection.According to the Enneking system, 13 patients were classified intoⅡA, and 9 patients into Ⅱ
B.All patients accepted chemotherapy before and after surgery. Results: All cases were followed up from 6 to 72 months (averaged，45.1
months). In 12 cases of ⅡA，one case (8.3%)developed pulmonary metastasis and died.One had a local recurrence，and underwent
amputation at the lower part of the femur．Ten cases remained continuously disease-free.In 9 cases of ⅡB，4 died ，and 5 remained
disease-free. Enncking staging was significantly affecting prognosis in patients. Conclusion: The surgical operation combined with the
osteoarticular allografts is an ideal treatment method for the proximal tibia osteosarcomas. |
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