周鸣彭建强△ 郭莹.基因治疗心肌缺血的载体应用新进展[J].,2011,11(12):2395-2397 |
基因治疗心肌缺血的载体应用新进展 |
Application of Different Vectors in Gene Therapyof Myocardial Ischemia |
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DOI: |
中文关键词: 基因治疗 心肌缺血 基因转移载体 |
英文关键词: Gene therapy Myocardial Ischemia Gene transfer vector |
基金项目:国家自然基金资助项目(30570073) |
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中文摘要: |
近年来,随着基因治疗技术的不断进步,为心肌缺血的治疗开辟了一条全新的途径,并取得了一些令人鼓舞的进展。基因治
疗主要包括治疗基因、基因转移载体以及基因导入途径三个方面。基因转移载体又在治疗基因和基因表达之间起着桥梁作用,因
此,发展安全、高效的基因转移系统是基因治疗的关键之一。目前用于基因治疗心肌缺血基因转移的载体主要有病毒载体和非病
毒载体。下面将就不同载体在心肌缺血的基因治疗中的应用进展进行简要的总结。 |
英文摘要: |
Recently, the progress of gene therapy technology has opened up a new way for the therapy of myocardial ischemia ,
and some inspiring developments have been achieved. Gene therapy includes theoretical gene, gene transfer vector and gene transfer
path. Gene transfer vector acts as the bridge between the others. Therefore ,develop a safe and efficient gene transfer system is the one
key of gene therapy. At present ,the mainly gene transfer vector for gene therapy of myocardial ischemia are viral vectors and non-viral
vectors. The article focused on recent application of different vectors in gene therapy of myocardial ischemia. |
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