| 邱忠礼孙娜王静周催车会莲.转基因棉籽亚慢性毒性的研究[J].,2011,11(12):2215-2220 |
| 转基因棉籽亚慢性毒性的研究 |
| Sub-Chronic Toxicity Study of Transgenic Cottonseed in SD Rats |
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| DOI： |
| 中文关键词: 转基因棉籽 30 天喂养 亚慢性毒性 |
| 英文关键词: Transgenic cottonseed 30-day feeding Sub-chronic toxicity |
| 基金项目:国家" 转基因生物新品种培育重大专项" 课题（2008ZX08011-006）资助 |
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| 中文摘要: |
| 目的：转基因棉籽对SD 大鼠亚慢性毒性的研究。方法：选取出生6-8 周的SPF 级SD 大鼠140 只，雌雄各半，按体重随机分
成7 组,分别连续饲喂含普通棉籽5 %、2.5 %和1.25 %的饲料和含转基因棉籽5 %、2.5 %和1.25 %的饲料以及基础饲料30 天。实
验过程中监测动物体重、进食量和进水量，结束后分别测定各组动物的血常规、血生化、脏体指数等指标。结果：实验期间各组动
物均生长发育良好，无中毒死亡现象发生。实验组实验动物的各项指标与对照组相比，无显著性差异（P≥0.05）。结论：本研究未
发现转基因棉籽对实验动物有亚慢性毒性。 |
| 英文摘要: |
| Objective: To monitor the effects of genetically modified cottonseed on nutritional status, physiological and
biochemical sub-chr- onic index in rats. Methods: A total of 140 six to eight - week-old SPF SD rats (male and female,half) were
randomly divided into 7 groups, continuously feeding the forage containing 5%, 2.5% and 1.25% normal cottonseed and transgenic
cottonseed as well as basal forage for 30 days,and then measuring indicators of body weight , food efficiency,blood routine and blood
biochemical parameters. Results: All the animals grow well and there is no poisoning and dead phenomenon during experimental time.
Indicators between experimental and control group show no significant difference （P≥0.05）. Conclusions：The study did not find
genetically modified cotton seeds has sub-chronic toxicity in experimental animals. |
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