| 刘晔赵亚娟王琴陆燕刘玉婷孙亚琴.妊娠期糖代谢异常对新生儿出生结局的影响[J].,2011,11(5):932-934 |
| 妊娠期糖代谢异常对新生儿出生结局的影响 |
| Effect of Abnormal Glucose Metabolism During Pregnancy on Outcomesin the Newborn |
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| DOI： |
| 中文关键词: 妊娠期糖尿病 糖代谢异常 糖耐量异常 新生儿 |
| 英文关键词: Gestaional diabetes mellitus Abnormal glucose metabolism Impaired glucose tolerance Newborn |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨妊娠期不同程度的糖代谢异常对胎儿发育及结局的影响。方法：前瞻性收集我院2009 年1 月至2010 年1 月分
娩的糖代谢异常的331 例单胎妊娠孕妇，分为糖筛查异常组69 例、糖耐量异常组126 例、妊娠期糖尿病（Gestaional Diabetes
Mellitus, GDM）组136 例，并选择同期糖代谢正常的751 例单胎孕妇为对照组，比较四组新生儿出生的最终结局。结果：糖筛查异
常组与对照组新生儿结局差异无显著性意义（P>0.05）；糖耐量异常组中巨大儿及新生儿窒息、早产儿的发生率与对照组差异有显
著性意义（P<0.05）；GDM 组与对照组差异有显著性意义（P<0.05）。结论：母亲妊娠期不同程度的糖代谢异常对新生儿影响不同。
口服葡萄糖耐量试验（Oral Glucose Tolerance Test, OGTT）异常与GDM 一样对新生儿发育及结局均有影响，可使巨大儿、新生儿
窒息、早产儿的发生率增高。 |
| 英文摘要: |
| Objective: To discuss the women with varing degree of abnormal glucose metabolism during pregnancy on outcomes
in the newborn. Methods: A prospective study on 331cases of singleton pregnancy and abnormal glucose metabolism during pregnancy:
69 GSA(Glucose Screening Abnormal),126 IGT(Impaired Glucose Tolerance),136 GDM(Gestaional Diabetes Mellitus),and 751 cases of
singleton pregnancy and normal glucose metabolism as control group from Jun 2009 to Jun 2010 in our Hospital, then contrasted the
outcomes of infants in the 4 groups. Results: No significant differences were found between GSA and control group (P>0.05); the rate of
giant baby, asphyxia of newborn, premature newborn were significant difference between IGT group and control group (P<0.05). The
GDM group compared with control group showing (P<0.05). Conclusion: Different degree of abnormal glucose metabolism during
pregnancy affect infants differently. The incidence of giant baby, asphyxia of newborn, premature newborn increased both in abnormal of
OGTT (oral glucose tolerance test) and GDM group. |
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