| 王辉1 张红超2 张江丽3.雾化吸入糖皮质激素治疗AECOPD的临床观察[J].,2011,11(4):735-737 |
| 雾化吸入糖皮质激素治疗AECOPD的临床观察 |
| Clinical Observation on Inhalation Efficacy of Corticosteroid forAcute Exacerbation of COPD |
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| DOI： |
| 中文关键词: 慢性阻塞性肺病 急性加重期 糖皮质激素 雾化吸入 |
| 英文关键词: chronic obstructive pulmonary disease acute exacerbation corticosteroid inhalation |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨雾化吸入糖皮质激素治疗慢性阻塞性肺病急性加重期（AECOPD）的临床效果。方法：60例AECOPD患者随机分
为治疗组和对照组，对照组给予抗感染、吸氧、化痰等常规治疗，治疗组在常规治疗的基础上给予糖皮质激素雾化吸入治疗，连续
治疗14d后评价临床疗效，观察治疗前后两组患者的临床症状和肺功能改善情况。结果：治疗组临床疗效有效率为96.7%，高于对
照组（80.0%），相比较有显著性差异（P<0.05）；治疗组临床症状评分和呼吸困难评分与治疗前和对照组比较显著下降，相比较有显
著性差异（P<0.05）；治疗组FEV1、FEV水平与治疗前和对照组比较显著上升，肺功能改善显著，相比较有显著性差异（P<0.05）。结
论：雾化吸入糖皮质激素治疗AECOPD疗效肯定，值得临床推广应用 |
| 英文摘要: |
| Objective: To evaluate the inhalation efficacy of corticosteroid in acute exacerbation of chronic obstructive pulmonary
disease（AECOPD）therapy. Methods: A total of 60 patients with AECOPD were randomly divided into treatment group and control
group. The control group was conventional treatment of antibiotics, oxygen, phlegm, and so on. On the basis of conventional treatment
the treatment group were given inhaled corticosteroid therapy. 14d after continuous treatment the clinical effect was evaluated, the clinical
symptoms and lung function of prior-treatment and post-treatment between two groups were observed. Results: The clinical efficiency
of the treatment group was 96.7%, the control group was 80.0%, compared the difference between two groups was significant (P <0.05);
The clinical symptoms and difficulty breathing scores of post-treatment were higher than prior-treatment and the control group, compared
the difference was significant (P <0.05); The FEV1 and FEV levels of the treatment group were higher than prior-treatment and the control
group, lung function improved significantly, compared the difference was significant (P <0.05). Conclusion: The inhaled corticosteroid
therapy is effective and worthy of clinical application. |
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