| 王海庆欧阳军△.不同液体复苏对失血性休克大鼠肠粘膜的影响[J].,2011,11(3):441-443 |
| 不同液体复苏对失血性休克大鼠肠粘膜的影响 |
| Effect of different fluid resuscitation on intestinal mucosa in rats withhemorrhagic shock |
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| DOI： |
| 中文关键词: 限制性液体复苏；失血性休克 ；肠粘膜 |
| 英文关键词: limited resuscitation haemorrhagic shock The intestinal mucosa |
| 基金项目:新疆石河子大学 |
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| 中文摘要: |
| 目的：观察不同液体复苏对失血性休克大鼠肠粘膜的影响以及肠粘膜的变化。方法：利用大鼠失血性休克模型以及不同的
补液方式，在复苏后120分钟时处死大鼠，取回肠4 cm，做病理切片并根据Chiu 等方法评估回肠黏膜上皮损伤指数。结果：液体
复苏组的肠粘膜损伤程度小于休克不补液组（p＜0.05）,而限制型液体复苏组的肠粘膜损伤程度小于充分液体复苏组（p＜0.05）。
结论：通过本实验对肠粘膜的观察可以得出，对于失血性休克，液体复苏时有效的抗休克方式，而对于复苏的方式来说，从肠黏膜
的保护方面来说，限制型液体复苏是优于传统的充分液体复苏的。 |
| 英文摘要: |
| Objective: To observe different fluid resuscitation of uncontrolled hemorrhagic shock rats intestinal mucosa and influence
of bowel mucosa changes. Methods: By using rat uncontrolled hemorrhagic shock model and different rehydration ways, the rats
were killed 120 minutes after recovery, taking the ileum 4 cm, doing pathological and according to the methods of assessment Chiu ileum
mu-cosal surfaces damage index. Results: fluid resuscitation group intestinal mucosa damage degree of less than shock not rehydration
group (p < 0.05), and restricted type fluid resuscitation group intestinal mucosa damage degree of less than large amounts of fluid resuscitation
group (p < 0.05). Conclusion: through the experiment of bowel mucosa observations can be concluded that the fluid resuscitation
for uncontrolled hemorrhagic shock, when effective way, but for resistance to shock recovery way, restricted type fluid resuscitation is
superior to the traditional fully fluid resuscitation. |
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