| 常珊1△ 焦雄2 王美华1 田绪红1.蛋白质氨基酸网络研究进展[J].,2011,11(1):190-193 |
| 蛋白质氨基酸网络研究进展 |
| Progress in Amino Acid Networks of Proteins |
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| DOI： |
| 中文关键词: 蛋白质 复杂网络 氨基酸网络 |
| 英文关键词: protein complex network amino acid network |
| 基金项目:国家自然科学基金（31070828），广东省科技计划项目（2010B080701070），华南农业大学校长基金（5600-k09325） |
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| 中文摘要: |
| 氨基酸网络是运用复杂网络工具对蛋白质结构- 功能关系研究的新方法。本文回顾了氨基酸网络中常用网络参量的计算方
法，如：度分布，聚集系数，平均最短路径等。结合本研究小组的工作，介绍了常用的网络构建和分析方法，并总结了氨基酸网络在
蛋白质折叠以及蛋白质分子对接问题中的应用。最后，分析了氨基酸网络研究目前存在的主要问题，并对未来的工作进行了展
望。 |
| 英文摘要: |
| Amino acid network is a new approach on the relationship between protein structure and function by using the technology
of complex network. In this article, we reviewed the computational methods of mainly network parameters in amino acid network,
such as the degree distribution, the clustering coefficient and the average minimal distance. Combining the research groups works, we
introduced the commonly used constructing and analyzing methods of amino acid network. Meanwhile, we concluded the application on
protein folding and protein docking. Finally, the existing major questions of amino acid network were analyzed and the prospects of the
future study were made. |
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