文章摘要
孙涛严金川陈小节梁仪赵建伟张朝普李璇.双核素心肌显像和门控心肌灌注显像检测糖尿病心肌病的临床应用[J].,2011,11(1):87-89
双核素心肌显像和门控心肌灌注显像检测糖尿病心肌病的临床应用
18F-FDG/99m Tc-MIBI Dual-Isotope SPECT and Gated Myocardial Imagingfor Viability and Function Assessment of Diabetic Cardiomyopathy
  
DOI:
中文关键词: 双核素同时采集  糖尿病心肌病  体层摄影术  发射型计算机  单光子
英文关键词: dual isotope simultaneous acquisition  diabetic cardiomyopathy  tomography  emission-computed  single-photon
基金项目:江苏大学临床医学科技发展基金资助(JLY20080004)
作者单位
孙涛严金川陈小节梁仪赵建伟张朝普李璇 江苏大学附属医院心内科 
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中文摘要:
      目的:采用一日法静息99mTc- 甲氧基异丁基异腈(MIBI)及18 F- 脱氧葡萄糖(FDG)双核素同时采集(DISA)心肌灌注代谢显 像与门控心肌灌注显像,评价糖尿病心肌病(DCM)患者心肌灌注、存活和心功能状况。方法:36 例临床诊断为DCM 患者,进行 99mTc-MIBI 和18F-FDG DISA 灌注代谢显像及门控心肌灌注显像。结果:36 例DISA 显像中, 26 例为灌注/ 代谢不匹配型,提示 心肌存活,10 例为灌注代谢匹配型,提示心肌梗死,无存活心肌,心功能正常患者30 例。结论:一日法DISA 心肌灌注/ 代谢显像与 门控法心肌灌注显像,可全面评价糖尿病心肌病患者的心肌灌注、存活及心功能状况。
英文摘要:
      Objective: To investigate the diagnostic value of rest 99mTc-MIBI/18 F-FDG dual isotope simultaneous acquisition (DISA) and gated myocardial imaging for viability and function assessment of patients with diabetic cardiomyopathy (DCM). Methods: Thirty-six patients of diabetic cardiomyopathy performed 18 F-FDG/99m Tc-MIBI DISA SPECT and gated myocardial imaging. Results: Among 36 DISA imagings, 26 cases were perfusion /metabolism mismatched and suggested viable myocardium,while 10 cases were perfusion /metabolism matched suggesting myocardium infarction. Conclusion: The same-day protocol of DISA and gated myocardial imaging study can well evaluate the myocardial viability and cardiac function for diabetic cardiomyopathy.
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